Karen T Liby Selected Research

2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid ethyl amide

11/2017	Synthetic oleanane triterpenoids enhance blood brain barrier integrity and improve survival in experimental cerebral malaria.
11/2010	Synthetic triterpenoids prolong survival in a transgenic mouse model of pancreatic cancer.

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Karen T Liby Research Topics

Disease

41	Neoplasms (Cancer) 01/2022 - 09/2004
15	Inflammation (Inflammations) 12/2020 - 02/2006
14	Breast Neoplasms (Breast Cancer) 01/2022 - 09/2004
13	Carcinogenesis 10/2021 - 02/2006
7	Lung Neoplasms (Lung Cancer) 10/2021 - 01/2014
6	Pancreatic Neoplasms (Pancreatic Cancer) 12/2020 - 03/2010
4	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 01/2022 - 01/2019
4	Neoplasm Metastasis (Metastasis) 10/2018 - 03/2011
4	Body Weight (Weight, Body) 11/2009 - 02/2006
3	Carcinoma (Carcinomatosis) 10/2015 - 03/2010
3	Chronic Disease (Chronic Diseases) 01/2014 - 01/2012
2	Melanoma (Melanoma, Malignant) 01/2022 - 03/2011
2	Pancreatitis 12/2020 - 12/2018
2	Obesity 01/2019 - 10/2009
2	Triple Negative Breast Neoplasms 01/2019 - 01/2014
2	Parkinson Disease (Parkinson's Disease) 01/2013 - 06/2009
2	Neuroinflammatory Diseases 07/2011 - 01/2011
1	Hyperplasia 01/2021
1	Hypertriglyceridemia 12/2020
1	Alopecia (Baldness) 01/2019
1	Hepatomegaly 01/2019
1	Cerebral Malaria 11/2017
1	Malaria 11/2017
1	Weight Loss (Weight Reduction) 01/2017
1	Leukemia 10/2015

Drug/Important Bio-Agent (IBA)

27	TriterpenesIBA 01/2022 - 02/2006
17	bardoxoloneIBA 11/2017 - 09/2004
15	1- (2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oyl) imidazoleIBA 12/2016 - 09/2004
11	bardoxolone methylIBA 01/2022 - 09/2004
8	oleananeIBA 11/2017 - 05/2007
6	Bexarotene (LGD1069)FDA Link 01/2022 - 01/2019
6	AcidsIBA 01/2022 - 09/2004
6	Pharmaceutical PreparationsIBA 12/2020 - 07/2015
6	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2009
5	EnzymesIBA 12/2018 - 01/2007
5	imidazoleIBA 03/2011 - 02/2006
4	Retinoid X Receptors (Retinoid X Receptor)IBA 01/2022 - 01/2019
4	vinyl carbamateIBA 10/2021 - 10/2015
4	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2021 - 07/2014
4	LG 100268IBA 01/2019 - 11/2010
4	CytokinesIBA 12/2018 - 01/2011
3	EstersIBA 01/2022 - 03/2010
3	talazoparibIBA 01/2021 - 01/2017
3	CarcinogensIBA 01/2019 - 10/2015
2	LigandsIBA 01/2022 - 01/2019
2	AntibodiesIBA 10/2021 - 01/2019
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2019
2	Estrogen ReceptorsIBA 01/2020 - 01/2013
2	LG 268IBA 01/2019 - 11/2010
2	Phosphotransferases (Kinase)IBA 10/2018 - 09/2013
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2018 - 01/2017
2	Cyclin D1IBA 10/2018 - 01/2012
2	2- cyano- 3,12- dioxooleana- 1,9(11)- dien- 28- oic acid ethyl amideIBA 11/2017 - 11/2010
2	Histone Deacetylase InhibitorsIBA 01/2016 - 01/2013
2	Vorinostat FDA Link 01/2016 - 01/2013
2	Carboplatin (JM8)FDA LinkGeneric 01/2016 - 01/2014
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2016 - 01/2014
2	Interleukin-17 (Interleukin 17)IBA 12/2014 - 01/2011
2	Messenger RNA (mRNA)IBA 01/2013 - 01/2011
2	Transcription Factors (Transcription Factor)IBA 01/2012 - 11/2009
2	Neuroprotective AgentsIBA 07/2011 - 06/2009
2	(2- cyano- 3,12- dioxooleana- 1,9- dien- 28- oic acid) trifluoroethylamideIBA 07/2011 - 01/2011
2	NF-E2-Related Factor 2IBA 07/2011 - 06/2009
2	Reactive Oxygen Species (Oxygen Radicals)IBA 03/2011 - 08/2006
2	AntioxidantsIBA 01/2011 - 11/2009
2	Oleanolic AcidIBA 01/2011 - 02/2006
2	Gemcitabine FDA Link 11/2010 - 03/2010
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2021
1	AgarIBA 01/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	INCB057643IBA 12/2020
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	Liposomes (Liposome)IBA 01/2019
1	CholesterolIBA 01/2019
1	OligopeptidesIBA 12/2018
1	AntigensIBA 12/2018
1	CeruletideIBA 12/2018
1	Protein Isoforms (Isoforms)IBA 10/2018
1	OximesIBA 10/2018
1	Antimalarials (Antimalarial Agents)IBA 11/2017
1	Immunomodulating AgentsIBA 11/2017
1	ArtesunateIBA 11/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2017
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2017
1	Proliferating Cell Nuclear Antigen (PCNA)IBA 01/2017
1	7- (2- (2,2- difluoroethoxy)- 3,5- di- tert- butylbenzene)- 3- methylocta- 2,4,6- trienoic acidIBA 01/2016
1	Dimethyl FumarateIBA 07/2015
1	Trastuzumab (Herceptin)FDA Link 01/2015
1	Lapatinib (GW572016)FDA Link 01/2015
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2015
1	Dextran SulfateIBA 12/2014
1	Sulfonic AcidsIBA 12/2014

Therapy/Procedure

9	Chemoprevention 03/2021 - 10/2005
6	Therapeutics 01/2021 - 07/2015
4	Oral Administration 09/2013 - 11/2009
3	Immunotherapy 01/2022 - 03/2010
2	Immunomodulation 01/2021 - 01/2019
1	Drug Therapy (Chemotherapy) 01/2021
1	Radical Mastectomy 01/2021